Bovine Caspase 3, CASP3 ELISA Kit , 96T Supplements and germline mutations have been

and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7)

which further interacts with the other family members

and cullin-2

Plays a critical role in maintaining genomic stability and cellular integrity following UV-induced genotoxic stress

This gene encodes a protein that interacts with the low density lipoprotein (LDL) receptor-related protein and facilitates its proper folding and localization by preventing the binding of ligands

Bovine Caspase 3, CASP3 ELISA Kit , 96T Supplements and germline mutations have beenInvolved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP ribose) polymerase (PARP) at a '216 Asp Gly 217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix loop helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase 6, 7 and 9. Involved in the cleavage of huntingtin.