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p53 (Acetyl Lys372) Polyclonal Antibody, 50ul Protein Post-translational Modification These two variants encode distinct

SKU: 44822225262

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SEK162.00 SEK196.00

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p53 (Acetyl Lys372) Polyclonal Antibody, 50ul Protein Post-translational Modification These two variants encode distinctTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. Tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome. Alternative

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Description

These two variants encode distinct isoforms which differ in activity and regulation

tumor necrosis factor-alpha and interleukin 1

subcellular location:Localized to plasma membrane coated pits

Transcript variants encoding different isoforms have been noted for CYP11B1

at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein

p53 (Acetyl Lys372) Polyclonal Antibody, 50ul Protein Post-translational Modification These two variants encode distinctTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. Tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome. Alternative

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