RAP1B Polyclonal Antibody, 100ul Bio-Reaction Tube Chromosomal translocation of this locus

Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias

such as this one

polyomavirus enhancer

The N-terminus is poorly conserved and may impart additional roles in developmental regulation| senescence| tumor suppression| cell growth control| and chemotaxis to each member of the family

BLK encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation

RAP1B Polyclonal Antibody, 100ul Bio-Reaction Tube Chromosomal translocation of this locusThis gene encodes a member of the RAS like small GTP binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin mediated cell signaling. This protein also plays a role in regulating outside in signaling in platelets. Alternate splicing results in multiple transcript variants.