Carcinoembryonic Antigen Monoclonal Antibody(10E1), 50ul Centrifugal Filter Mutations in NRL have been

Mutations in NRL have been associated with retinitis pigmentosa and retinal degenerative diseases

CD244 encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing

The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator

Negatively regulates the PAK1 kinase

2004 [PubMed 14701734])

Carcinoembryonic Antigen Monoclonal Antibody(10E1), 50ul Centrifugal Filter Mutations in NRL have beenThis gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on