GIT1 Polyclonal Antibody, 20ul Cell Transfection Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding multiple isoforms have been observed for CUL3

and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells

ediates cell-cell adhesion in a calcium-dependent manner (By similarity)

transferring phosphorus-containing groups and protein tyrosine kinase activity

thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery

GIT1 Polyclonal Antibody, 20ul Cell Transfection Alternatively spliced transcript variants encodingARF GTPase activating protein GIT1 is an enzyme that in humans is encoded by the GIT1 gene. GIT1 contains an ARFGAP domain, Anykrin repeats and a GRK interacting domain. The Arf GAP domain, which enables it to act as a GTPase activating protein (GAP) for the Arf family of GTPases, has been shown to be involved in phosphorylation and inhibition of the ADRB2. If synaptic localization of GIT1 is disturbed, then this is known to affect dendritic spine