DKK4 Polyclonal Antibody, 20ul Vector Construction Genetic variation in this gene

Genetic variation in this gene influences susceptibility to occlusive vascular disease

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in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor

The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation

It also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner

DKK4 Polyclonal Antibody, 20ul Vector Construction Genetic variation in this geneThis gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. Activity of this protein is modulated by binding to the Wnt co receptor and the co factor kremen 2.