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The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression

subcellular location:Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle

GO annotations related to this gene include hydrolase activity and serine-type peptidase activity

and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization

USP30 Polyclonal Antibody, 50ul Bottle-Top Dispenser Unlock the full potential ofUSP30, a member of the ubiquitin specific protease family (see USP1, MIM 603478), is a novel mitochondrial deubiquitinating (DUB) enzyme.