p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11722] Nucleic Acid Isolation & Purification Desmocollins

Desmocollins

also known as AGBL2 (ATP/GTP binding protein-like 2)

The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import

The encoded protein may play a role in regulating p53-mediated apoptosis

Defects in this gene can cause emphysema or liver disease

p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11722] Nucleic Acid Isolation & Purification DesmocollinsThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative