MMAC Rabbit Polyclonal Antibody, 50ul Stepper This region is commonly deleted

This region is commonly deleted in chronic lymphocytic leukemia

Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity

This gene belongs to the SMC3 subfamily of SMC proteins

miscellaneous:This chain binds calcium

Involved in embryogenesis and hematopoiesis

MMAC Rabbit Polyclonal Antibody, 50ul Stepper This region is commonly deletedThe exact function of the protein encoded by this gene is not known however its C terminal region shows similarity to TonB a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.