AR Polyclonal Antibody, 20ul[BT-AP00399] Fluorescent Staining MAP4K3 encodes a member of

MAP4K3 encodes a member of the mitogen-activated protein kinase kinase kinase kinase family

Desumoylated by SENP2

It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors

It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form

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AR Polyclonal Antibody, 20ul[BT-AP00399] Fluorescent Staining MAP4K3 encodes a member ofThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This