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Rat Midkine, MDK ELISA Kit, 96T Pipette Holder Interaction with LRRC32/GARP controls activation

SKU: 50285709555

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Rat Midkine, MDK ELISA Kit, 96T Pipette Holder Interaction with LRRC32/GARP controls activationDevelopmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen activated protein kinase (MAPK) and PI3 kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by

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Description

Interaction with LRRC32/GARP controls activation of TGF-beta-1 on the surface of activated regulatory T-cells (Tregs) (By similarity)

3'-triiodothyronine

this then triggers calcium ion release into the cytosol

The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages

This domain is often found in proteins that are involved in membrane trafficking and signal transduction

Rat Midkine, MDK ELISA Kit, 96T Pipette Holder Interaction with LRRC32/GARP controls activationDevelopmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen activated protein kinase (MAPK) and PI3 kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by

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