ERK 8(Phospho Thr175/Y177) Polyclonal Antibody, 50ul Bio-Reaction Tube Similar to STAM| this protein

Similar to STAM| this protein acts downstream of JAK kinases| and is phosphorylated in response to cytokine stimulation

This gene encodes the E3 binding protein subunit

Translocated to the nucleus on Ser-151 dephosphorylation

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ERK 8(Phospho Thr175/Y177) Polyclonal Antibody, 50ul Bio-Reaction Tube Similar to STAM| this proteinCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,The N terminal region (1 20) is the minimal region necessary for ubiquitination and further proteosomal degradation.,The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.,enzyme regulation: Activated by threonine and tyrosine phosphorylation. Inhibited by dual specificity phosphatases, such as DUSP1.,In vitro, phosphorylates MBP.,PTM: