FEN-1 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation This protein cleaves and activates

This protein cleaves and activates caspases 3 and 7

This protein preferentially induces apoptosis in transformed and tumor cells

Adapter protein that links FGR and NGF receptors to downstream signaling pathways

The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage

This encoded protein may play a role in protein kinase C signaling

FEN-1 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation This protein cleaves and activatesFlap endonuclease 1 encoded by FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG RAD2 endonuclease family and is