SLUG Monoclonal Antibody, 100ul Mammalian Expression Exon 1 encodes the leader

Exon 1 encodes the leader peptide| exons 2 and 3 encode the two extracellular domains| exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail

It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters

The expression of MYL7 in heart is predominatantly restricted to the atrium

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and it contributes to spinal sensitization and neuropathic pain states

SLUG Monoclonal Antibody, 100ul Mammalian Expression Exon 1 encodes the leaderThis gene encodes a member of the Snail family of C2H2 type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E box motifs and is also likely to repress E cadherin transcription in breast carcinoma. This protein is involved in epithelial mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.