ALKB2 Polyclonal Antibody, 100ul Gene Synthesis Two alternatively spliced variants encoding

Two alternatively spliced variants encoding distinct isoform

Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane

The protein encoded by LAMA3 belongs to the laminin family of secreted molecules

Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB)

The encoded protein interacts with the cullin-3 protein

ALKB2 Polyclonal Antibody, 100ul Gene Synthesis Two alternatively spliced variants encodingThe Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1 methyladenine and 3 methylcytosine (Duncan et al., 2002