Gab 2(Phospho Ser159) Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) The BRCA2-Associated Factor 35 (BRAF35)

The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2

recessive disease characterized by immune dysregulation and microthrombocytopenia

This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes

The protein may play a role in cell growth and differentiation and act as a negative growth regulator

Interacts with KFL1 (By similarity)

Gab 2(Phospho Ser159) Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) The BRCA2-Associated Factor 35 (BRAF35)This gene is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol 3 kinase in