TRML2 Polyclonal Antibody, 20ul Sealing Film Alternative splicing produces both membrane-bound

Alternative splicing produces both membrane-bound and soluble proteins

This gene encodes a member of the glutaredoxin family

Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6

Mutation of this gene is associated with acute myeloid leukemia

The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors

TRML2 Polyclonal Antibody, 20ul Sealing Film Alternative splicing produces both membrane-boundTREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003