UBP18 Rabbit Polyclonal Antibody, 50ul Yeast Expression kidney and intestine

kidney and intestine

The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains| Fbls containing leucine-rich repeats| and Fbxs containing either different protein-protein interaction modules or no recognizable motifs

Transcript heterogeneity due to alternative polyadenylation has been noted for this gene

the first region lacks the essential Glu active site residue at position 241

also known as Amish nemaline myopathy

UBP18 Rabbit Polyclonal Antibody, 50ul Yeast Expression kidney and intestineThe protein encoded by this gene belongs to the ubiquitin specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin like protein) fusions and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues indicating that this protein is a major