MC2-R Polyclonal Antibody, 50ul Drug Development and Evaluation BRE is upregulated in several

BRE is upregulated in several types of cancer

GABRD encodes the delta subunit

This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain

A related pseudogene is located on chromosome 9

This enzyme is involved in the metabolism of approximately half the drugs in use today

MC2-R Polyclonal Antibody, 50ul Drug Development and Evaluation BRE is upregulated in severalMC2R encodes one member of the five member G protein associated melanocortin receptor family. Melanocortins (melanocyte stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.