Rat Cerebral Dopamine Neurotrophic Factor, CDNF ELISA Kit, 96T Cell Separation and Collection Mutations in this gene result

Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus

In addition to its chemotactic and angiogenic properties

involved in class-switch recombination (CSR) by controlling the expression of both AICDA and of germline transcripts of the intervening heavy-chain region and constant heavy-chain region (I(H)-C(H))

taurine biosynthesis

Catalyzes also the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2 (PubMed: 12244105

Rat Cerebral Dopamine Neurotrophic Factor, CDNF ELISA Kit, 96T Cell Separation and Collection Mutations in this gene resultTrophic factor for dopamine neurons. Prevents the 6 hydroxydopamine (6 OHDA) induced degeneration of dopaminergic neurons. When administered after 6 OHDA lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.