CD43 Rabbit Polyclonal Antibody, 100ul Gene Synthesis Mutations in EPAS1 are associated

Mutations in EPAS1 are associated with erythrocytosis familial type 4

PROM1 encodes a pentaspan transmembrane glycoprotein

Upon stimulation by inositol 1

which overlaps in some cases

PITPNB encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes

CD43 Rabbit Polyclonal Antibody, 100ul Gene Synthesis Mutations in EPAS1 are associatedThe protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes T lymphocytes monocytes granulocytes and some B lymphocytes. It may be part of a physiologic ligand receptor complex involved in T cell activation. During T cell activation this protein is actively removed from the T cell APC (antigen presenting cell) contact site suggesting a negative regulatory role in adaptive immune response.