PHLP1 Polyclonal Antibody, 20ul PCR Series Diseases associated with TPT1 include

Diseases associated with TPT1 include urticaria and allergic hypersensitivity disease

This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans

This protein is involved in the elongation of long-chain polyunsaturated fatty acids

Among its related pathways are Creation of C4 and C2 activators and Regulation of actin dynamics for phagocytic cup formation

Cowden syndrome

PHLP1 Polyclonal Antibody, 20ul PCR Series Diseases associated with TPT1 includeThis gene encodes a member of the serine threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt mediated insulin signaling.