Human Beta, Beta-Carotene 9', 10'-Oxygenase, BCO2 ELISA Kit, 96T Vortex Mixer and encoded by one gene

and encoded by one gene

This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C| 1

MED29 is a subunit of the Mediator complex

but not in muscle (PubMed: 17908561)

These enzymes hydrolyze a variety of dipeptides| including leukotriene D4| the beta-lactam ring of some antibiotics| and cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation (Habib et al

Human Beta, Beta-Carotene 9', 10'-Oxygenase, BCO2 ELISA Kit, 96T Vortex Mixer and encoded by one geneAsymmetrically cleaves beta carotene at the 9',10' double bond resulting in the formation of beta apo 10' carotenal and beta ionone. Besides beta carotene, lycopene is also oxidatively cleaved. The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects.