Mouse Bone Morphogenetic Protein Receptor Type-1B, BMPR1B ELISA Kit , 96T Pathway and Network Analysis normal development of Leydig cells

normal development of Leydig cells and spermatogenesis

May act as a KRAS effector protein

Promotes colon cancer cell migration and invasion in an integrin alpha-6/beta-1-dependent manner through activation of Rac1

Plays a role in keratinocyte migration during wound healing

May play a role in liver regeneration

Mouse Bone Morphogenetic Protein Receptor Type-1B, BMPR1B ELISA Kit , 96T Pathway and Network Analysis normal development of Leydig cellsOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7 OP 1. Receptor for GDF5 (PubMed: 26105076, PubMed: 19229295). Positively regulates chondrocyte differentiation through GDF5 interaction (PubMed: 24098149).