ER alpha(Phospho Ser305) Polyclonal Antibody, 20ul Lysosome Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants have been identified

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whereas elongins B and C are regulatory subunits

The mature protein begins at aa 100 and has a 542 aa extracellular region

In addition| the CXXC domain of this protein has been shown to bind unmethylated CpG dinucleotides| localize to promoters and CpG islands| and interact with the catalytic domain of methylcytosine dioxygenase ten-eleven-translocation 2| an iron and alpha-ketoglutarate-dependent dioxygenase that modifies the methylation status of DNA

ER alpha(Phospho Ser305) Polyclonal Antibody, 20ul Lysosome Multiple alternatively spliced transcript variantsThis gene encodes an estrogen receptor, a ligand activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen