Integrin AlphaL Polyclonal Antibody, 50ul Primary Antibodies Several alpha defensin genes are

Several alpha defensin genes are clustered on chromosome 8

Mutations in this gene have been associated with dystonia

It binds to integrins of type CD11a / CD18

This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression

Contains 2 RanBD1 domains

Integrin AlphaL Polyclonal Antibody, 50ul Primary Antibodies Several alpha defensin genes areITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function associated antigen 1 (LFA 1), which is expressed on all leukocytes. LFA 1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1 3