DNA pol Epsilon 4 Polyclonal Antibody, 50ul Organelle Studies a highly penetrant familial cancer

a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53

a reduction in germ cell numbers

indicating that the encoded protein might also represent a transcription factor

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DNA pol Epsilon 4 Polyclonal Antibody, 50ul Organelle Studies a highly penetrant familial cancerPOLE4 is a histone fold protein that interacts with other histone fold proteins to bind DNA in a sequence independent manner. These histone fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.