JIP-1(Phospho Thr103) Polyclonal Antibody, 100ul Aspirating Pipets 1 gene family encodes a

1 gene family encodes a group of multifunctional cytoskeletal proteins (4

|Transcriptional activator which triggers apoptosis in the absence of survival factors| including neuronal cell death upon oxidative stress

It is highly expressed in the adrenal gland and testis

susceptibility to idiopathic Parkinson's disease

In the rest of the brain a basal expression seems to be always present

JIP-1(Phospho Thr103) Polyclonal Antibody, 100ul Aspirating Pipets 1 gene family encodes aThis gene encodes a regulator of the pancreatic beta cell function. It is highly similar to JIP 1, a mouse protein known to be a regulator of c Jun amino terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL 1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA binding transactivator of the glucose