ABR Rabbit Polyclonal Antibody, 50ul Cryopreservation Plectin is expressed as several

Plectin is expressed as several protein isoforms in a wide range of cell types and tissues from a single gene located on chromosome 8 in humans (PMID: 8633055

This gene encodes antizyme 3

Proinflammatory cytokine favoring Th2-type immune responses

A similar duplicated gene is located next to this gene on chromosome 16

where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering

ABR Rabbit Polyclonal Antibody, 50ul Cryopreservation Plectin is expressed as severalThis gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase activating protein domain, a domain found in members of the Rho family of GTP binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene.