RUNX2 Polyclonal Antibody, 20ul[BT-AP08061] Dry Bath Alternative splicing results in a

Alternative splicing results in a multitude of transcript variants

Mutations in this gene result in disorders of male secondary sexual character development

The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases

and its upregulation during differentiation

an autosomal dominant form of genetic hair loss

RUNX2 Polyclonal Antibody, 20ul[BT-AP08061] Dry Bath Alternative splicing results in aRUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA binding domain. Runt related transcription factor 2 is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions