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11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia

and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B

Several transcript variants encoding the same protein have been found for this gene

suggesting that the function of this gene may be signal repression

CDX2 Monoclonal Antibody(14H6), 20ul PCR Series Say goodbye to messy spillsThis gene is a member of the caudal related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.