CD63 Polyclonal Antibody, 50ul[BT-AP02478] Molecular Sciences Mutations in ACTA1 cause nemaline

Mutations in ACTA1 cause nemaline myopathy type 3

Belongs to the small heat shock protein (HSP20) family

TBX3 (T-box 3) is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain

PYCARD encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD)

a transcription factor which is activated by androgen and has a key role in male sexual differentiation

CD63 Polyclonal Antibody, 50ul[BT-AP02478] Molecular Sciences Mutations in ACTA1 cause nemalineKRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate sized filaments in the cytoplasm of epithelial cells. The product of KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single layered epithelial cells. Keratin 8 plays a role in maintaining cellular structural integrity and also functions in signal transduction