AIRE-1 Polyclonal Antibody, 50ul[BT-AP00311] DNA Synthesis Tyrosine phosphorylation seems to occur

Tyrosine phosphorylation seems to occur only at the plasma membrane

which are involved in microtubule assembly and important for neurogenesis

Mutations in MT-CO1 have been associated with Leber's hereditary optic neuropathy (LHON)

The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide

This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors

AIRE-1 Polyclonal Antibody, 50ul[BT-AP00311] DNA Synthesis Tyrosine phosphorylation seems to occurAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and