FAS-L Polyclonal Antibody, 20ul[BT-AP15532] sgRNA customized design Mutations in APP have been

Mutations in APP have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy)

Homologues of the notch-ligands have also been identified in human

and may play an important role in regulating insulin gene expression

The rat protein can also interact with alpha-actinin-4

and is capable of activating the classical complement pathway

FAS-L Polyclonal Antibody, 20ul[BT-AP15532] sgRNA customized design Mutations in APP have beenThis gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS FASLG signaling pathway is essential for immune system regulation, including activation induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be