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Sgo1 Polyclonal Antibody, 100ul Fluorescent Staining The protein encoded by VIP

SKU: 64163753395

4.6
USD141.00 USD172.00

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Sgo1 Polyclonal Antibody, 100ul Fluorescent Staining The protein encoded by VIPShugoshin like 1 encoded by SGOL1 is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found

Store: cgm.lt · Domain: cgm.lt

Description

The protein encoded by VIP (vasoactive intestinal peptide) belongs to the glucagon family

Abnormal expression of VWA5A may lead to an increase in adhesion of CNE-2L2 cells associated with an increase in expression of E-cadherin

RUNX proteins form a heterodimeric complex with CBFβ which confers increased DNA binding and stability to the complex

The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA

and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B

Sgo1 Polyclonal Antibody, 100ul Fluorescent Staining The protein encoded by VIPShugoshin like 1 encoded by SGOL1 is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found

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