Rock-2 Polyclonal Antibody, 100ul[BT-AP07971] Enzyme Activity Assays this loss is due to

this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation

TNNI3K encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases

an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline

and in subcellular localization

This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression

Rock-2 Polyclonal Antibody, 100ul[BT-AP07971] Enzyme Activity Assays this loss is due toRho associated protein kinase 2 encoded by ROCK2 is a serine threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.