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APLP-1 Polyclonal Antibody, 100ul Thermal Control This gene is a member

SKU: 64848674863

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APLP-1 Polyclonal Antibody, 100ul Thermal Control This gene is a memberAPLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid like protein 1 is a membrane associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development.

Store: cgm.lt · Domain: cgm.lt

Description

This gene is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases)

In migrating cells

It is a C-type lectin with mannose binding specificity

The product of MED13 is proposed to form a sub-complex with MED12

An important paralog of this gene is HAP1

APLP-1 Polyclonal Antibody, 100ul Thermal Control This gene is a memberAPLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid like protein 1 is a membrane associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development.

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