DU4L7 Rabbit Polyclonal Antibody, 20ul Metabolic enzymes tool compounds Sodium/potassium-transporting ATPase subunit alpha-1 encoded

Sodium/potassium-transporting ATPase subunit alpha-1 encoded by ATP1A1 belongs to the family of P-type cation transport ATPases

It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function

An important paralog of this gene is SERINC2

Several transcript variants encoding different isoforms have been found for NCOA3

and Familial dysautonomia

DU4L7 Rabbit Polyclonal Antibody, 20ul Metabolic enzymes tool compounds Sodium/potassium-transporting ATPase subunit alpha-1 encodedThis gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT PCR and in vitro expression