BHE40 Rabbit Polyclonal Antibody, 50ul Centrifuges The protein links integrin subunits

The protein links integrin subunits to the tyrosine kinase FYN

The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329)

CAs show extensive diversity in their distribution and subcellular localization

The encoded protein is also a putative tumor suppressor protein| and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia

The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs)| and functions as a mediator of the anti-apoptotic signals from TNF receptors

BHE40 Rabbit Polyclonal Antibody, 50ul Centrifuges The protein links integrin subunitsThis gene encodes a basic helix loop helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E box binding sites in the promoter of PER1 and repress CLOCK ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation.