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AR Polyclonal Antibody, 50ul[BT-AP00566] Sampling Tubes This gene encodes a member

SKU: 65798441687

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SEK162.00 SEK193.00

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AR Polyclonal Antibody, 50ul[BT-AP00566] Sampling Tubes This gene encodes a memberThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR

Store: cgm.lt · Domain: cgm.lt

Description

This gene encodes a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide| cysteine-rich/furin-like domain| thrombospondin domain and a C-terminal basic region

Mutations in this gene have been associated with Niemann-Pick disease| type C2 and frontal lobe atrophy

The encoded protein contains three extracellular C2-like immunoglobulin domains

which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region

ALCAM encodes activated leukocyte cell adhesion molecule (ALCAM)

AR Polyclonal Antibody, 50ul[BT-AP00566] Sampling Tubes This gene encodes a memberThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR

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