IFFO1 Rabbit Polyclonal Antibody, 100ul Plasma Loss of function or expression

Loss of function or expression of this gene is associated with decreased apoptosis

Similar to hexokinases 1 and 2

an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy

PYCARD encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD)

Diseases associated with ZDHHC2 include hepatocellular carcinoma and locked-in syndrome

IFFO1 Rabbit Polyclonal Antibody, 100ul Plasma Loss of function or expressionThis gene is a member of the intermediate filament family. Intermediate filaments are proteins which are primordial components of the cytoskeleton and nuclear envelope. The proteins encoded by the members of this gene family are evolutionarily and structurally related but have limited sequence homology, with the exception of the central rod domain. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this