TPOR(Phospho-Tyr626) Rabbit Polyclonal Antibody, 50ul Immunology Involved in the RCC1/Ran-GTPase pathway

Involved in the RCC1/Ran-GTPase pathway

Mutations in this gene have been associated with hereditary hemochromatosis type III

CMTM6 belongs to the chemokine-like factor gene superfamily

The checkpoint kinase 2 encoded by CHEK2 is a cell cycle checkpoint regulator and putative tumor suppressor

Alternatively spliced transcript variants encoding the same protein have been found for this gene

TPOR(Phospho-Tyr626) Rabbit Polyclonal Antibody, 50ul Immunology Involved in the RCC1/Ran-GTPase pathwayIn 1990 an oncogene v mpl was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue named c mpl was cloned. Sequence data revealed that c mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti sense oligodeoxynucleotides of c mpl inhibited megakaryocyte colony