MAST4 Polyclonal Antibody, 100ul Metabolic enzymes Mutations in this gene are

Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A

because the active site serine and histidine residues are replaced

The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers

and thus mediates the anti-apoptotic signals from TNF receptors

This gene has been shown to repress lamellipodial extension and focal adhesion turnover| and is thought to regulate cell motility

MAST4 Polyclonal Antibody, 100ul Metabolic enzymes Mutations in this gene areMAST4 encodes a member of the microtubule associated serine threonine protein kinases. The proteins in this family contain a domain that gives the kinase the ability to determine its own scaffold to control the effects of their kinase activities. Alternative splicing results in multiple transcript variants encoding different isoforms.