Rat C-C Chemokine Receptor Type 2, CCR2 ELISA Kit, 96T Cell Biology reorganization of the actin cytoskeleton
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Rat C-C Chemokine Receptor Type 2, CCR2 ELISA Kit, 96T Cell Biology reorganization of the actin cytoskeletonKey functional receptor for CCL2 but can also bind CCL7 and CCL12 (By similarity). Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (By similarity) Also acts as a receptor for the beta defensin DEFB106A DEFB106B (By similarity). Regulates the expression of T cell inflammatory cytokines and T cell
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