Insulin R Polyclonal Antibody, 20ul[BT-AP04565] Cell Culture Flasks Heat shock cognate 71 kDa

Heat shock cognate 71 kDa protein belongs to the latter group

Mutations ALMS1 cause Alstrom syndrome

Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound

is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules

The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function

Insulin R Polyclonal Antibody, 20ul[BT-AP04565] Cell Culture Flasks Heat shock cognate 71 kDaINSR encodes a member of the receptor tyrosine kinase family of proteins. Insulin receptor is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited