LRRK2 Polyclonal Antibody, 50ul Miscellaneous Expression of CIAPIN1 is dependent

Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al

It is primarily an alpha-helical protein with very little coiled coil| and binds directly to the largest subunit (p150) of dynactin

Keratin 18

Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein)

In the developing cortex| cortical neurons must migrate over long distances to reach the site of their final differentiation

LRRK2 Polyclonal Antibody, 50ul Miscellaneous Expression of CIAPIN1 is dependentThis gene is a member of the leucine rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine rich repeat (LRR) domain, a kinase domain, a DFG like motif, a RAS domain, a GTPase domain, a MLK like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease 8.