HP-1 Gamma mouse Monoclonal Antibody(3B9), 50ul Human Genome Knockout Libraries These glycosylases initiate the first

These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al

suggesting a function in tumor invasion

Increased expression of this gene is associated with colorectal cancer

HIST4H4 is intronless and encodes a replication-dependent histone that is a member of the histone H4 family

This complex binds to the promoters of snRNA genes transcribed by either RNA polymerase II or III and recruits other regulatory factors to activate snRNA gene transcription

HP-1 Gamma mouse Monoclonal Antibody(3B9), 50ul Human Genome Knockout Libraries These glycosylases initiate the firstAt the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds