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CD63 Polyclonal Antibody, 50ul[BT-AP01816] Mini dry bath Under basal conditions the encoded

SKU: 71304455103

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CD63 Polyclonal Antibody, 50ul[BT-AP01816] Mini dry bath Under basal conditions the encodedKRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in KRT18 have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for KRT18.

Store: cgm.lt · Domain: cgm.lt

Description

Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm

This protein belongs to the Pmr5-Cas1p-esterase subfamily in that it contains the catalytic triad comprised of serine| aspartate and histidine and lacks two conserved regions (glycine after strand S2 and GxND motif)

In addition to being highly expressed in the prostate it is also expressed in the bladder

and tropomyosin

|Component of a protein kinase signal transduction cascade

CD63 Polyclonal Antibody, 50ul[BT-AP01816] Mini dry bath Under basal conditions the encodedKRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in KRT18 have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for KRT18.

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