SIRT1 (GlcNAc D548) Rabbit Polyclonal Antibody, 50ul Multi-Layer Cell Culture System and maintenance of genomic stability

and maintenance of genomic stability

This enzyme acts on histones| and its activity is important for chromatin assembly and chromosome integrity

Mutations in ITPR1 cause spinocerebellar ataxia type 15

kidney or liver

This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members

SIRT1 (GlcNAc D548) Rabbit Polyclonal Antibody, 50ul Multi-Layer Cell Culture System and maintenance of genomic stabilityThis gene encodes a member of the sirtuin family of proteins homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular