p53 Monoclonal Antibody(6C4), 50ul Cell Biology CYP1B1 encodes a member of

CYP1B1 encodes a member of the cytochrome P450 superfamily of enzymes

The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors

Allelic variants are associated with prostate and brain cancer susceptibility

Activity of this protein is modulated by binding to the Wnt co-receptor and the co-factor kremen 2

The encoded protein contains multiple conserved functional domains

p53 Monoclonal Antibody(6C4), 50ul Cell Biology CYP1B1 encodes a member ofThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.